Designs for Health Australia presents this important Webinar:
Quatrefolic: The Next Gen Bioavailable Folate
Research and Evidence in Cognitive, Mood, and Cardiovascular Health
Presentation + Live Q & A Discussion
Prof. Luca Tiano and Lea McIntyre ND
Download Webinar Slides:–
Engage in evidence-based practitioner education
Luca Tiano, respected Professor of Nutrigenetic and Nutrigenomics at the Polytechnic University of Marche, presents the benefits of Quatrefolic®, the biologically active form of folate absorbed directly by the body.
Prof Tiano demonstrates how, in vivo, the body converts dietary folic acid and food folates to 5-MTHF (also named L-methylfolate or 5-methyltetrahydrofolate) through a multi-step process where the methylenetetrahydrofolate reductase (MTHFR) enzyme provides a key role.
Learn the Value of Active Folate vs Folic Acid:
Every human needs folate, so it’s important to understand this essential vitamin (Vitamin B9) and the relevance of its different forms.
- How Metilfolate, the active folate, as Quatrefolic®, is the folate form effective in the body without the need for additional metabolic processing.
- Understand the mechanism of action of active folate (5-MTHF).
- How Quatrefolic can be used to support reproductive stages, homocysteine metabolism, cardiovascular health, mood and brain functioning, and more.
- The importance of folate in pregnancy and fertility, explicitly focusing on the advantage of (6S)5-MTHF supplementation versus folic acid.
- Why maintaining correct folate levels in the body is of primary importance, particularly in specific stages of life, like pregnancy and during childbearing age.
Bioavailability of Folates
In recent years, an increasing interest in understanding the different forms of folates has emerged both from the scientific and practitioner community.
Luca Tiano will review the latest research about active folates:
- The physiological roles and sources of folate
- Folate metabolism
- Folate deficiency and related health issues
- Populations at risk for folate deficiency and its leading causes
- Supplementation with folic acid
Folate deficiency:
A risk factor for age-related cognitive decline
Folate (vitamin B9) is one of the most critical substances investigated for its potential to slow or reverse age-related cognitive decline, especially in the elderly, helping to counteract the onset of dementia through its interaction with the neurotoxic substance homocysteine (Hcy).
The highest folate deficiency rates in the population occur among older adults, with estimated prevalence rates ranging from 5% to 20%. The prevalence of folate deficiency is high among individuals aged over 65 years, mainly due to reduced dietary intake, intestinal malabsorption, and metabolism defects that affect a part of the population due to enzyme polymorphisms.
Learn From Prof. Luca Tiano’s
Scientific and Research Experience
Luca Tiano, PhD.
Scientist, Researcher, Educator
Since 1997, Prof. Luca Tiano has been involved in research on oxidative stress and using antioxidants in cellular models or in vivo, both under physiological conditions or in pathologies associated with an altered redox status. In 2003 he started to work at the Polytechnic University of Marche Ancona at the Department of Clinical Sciences, where he was involved in joint research projects with Children’s Hospital, Salesi and the Heart Institute, Lancisi.
In 2016 he was appointed Professor of Biochemistry at the Department of Life and Environmental Sciences. Prof. Tiano supervises research activities in Oxidative Stress and Ageing laboratory, where he coordinates four postdoc researchers and supervises several Master’s and PhD students. The main research activities of the laboratory concern the health effects of lipophilic cofactors (Coenzyme Q10 and Vitamin K) in healthy subjects and under pathological conditions associated with enhanced oxidative stress, with a special focus on cardiovascular health, muscle function and sarcopenia, skin ageing and photoaging.
Prof. Tiano’s laboratory research deals with the bioavailability and biological effects of vitamins and antioxidants in nutritional supplements and functional foods. This research has led to active collaborations with biotechnology industries, as well as food supplement, cosmetic and pharmaceutical companies.
Prof. Tiano teaches Protein Biochemistry, Nutrigenetics and a focus course on Oxidative stress in Biological systems at the Department of Life and Environmental Sciences, UNIVPM. Author of 154 papers in international peer-reviewed journals (Hi 30, Cit 3544). Board member of the European Society of Comparative Biochemistry and Physiology; Executive Committee Member of the International Coenzyme Q10 Association; President of the Italian Section of the International Coenzyme Q10 Association, Founder of the academic Spinoff company of the Polytechnic University of Marche QFarm s.r.l. Innovative startup specialised in the development of functional food and functional feed for human and animal wellbeing.
Meet Your Webinar Host
Lea McIntyre ND
Designs for Health Australia
Lea McIntyre is Technical Marketing Manager at Designs for Health Australia.
Lea has 20 years of experience as a qualified naturopath, herbalist and nutritionist. In her clinical practice, she specialises in paediatric and gut health and the relationship between inflammation and neurological conditions.
Lea provides direct support for DFH Practitioners – and frequently provides guidance on FX Medicine Test reports.