CASI Introduction

David M. Brady, ND, DC, CCN, DACBN, IFMCP, FACN

KEYNOTE: Lyme Disease & Stealth Infections: The Current State of Diagnosis and Treatment

Richard Horowitz, MD

Lyme disease, associated co-infections, and vector-borne diseases are increasing in epidemic proportions and are expected to worsen with climate changes and the rising global temperature. These infections are responsible for chronic fatigue, musculoskeletal and neuropsychiatric manifestations which can overlap many other chronic illnesses, including CFS/ME, fibromyalgia, auto-immune illness including RA and MS, and long COVID. This session will focus on the clinical manifestations of these illnesses, laboratory testing, and differential diagnosis, as well as new effective pharmaceutical and nutraceutical treatment options.

Diagnosis, Treatment, and Immunopathogenesis of Chronic Inflammation, including COVID-19 Long-Haul

Bruce Patterson, MD

In this one-hour impactful session, you will learn about the status of laboratory testing (including cytokine, proteome, and metabolome signatures), as well as the resulting recommended treatment protocols for Long-Haul COVID.

Cardiovascular Implications Of Infectious Diseases (SARS-CoV-2 And Vascular Immune Dysfunction)

Mark Houston, MD

Acute and chronic infections can induce cardiovascular diseases such as coronary heart disease, myocarditis, congestive heart failure, and hypertension. The severity, chronicity, type of infection, patient’s underlying immune function and health, and the total infectious disease burden are some of the factors that result in cardiovascular outcomes. In this lecture, Dr Houston reviews the pathophysiology, clinical presentations, evaluation, and treatment of infections and cardiovascular disease.

Managing Pediatric Post-Infectious Syndromes, including PANS and PANDAS

Lindsay Wells, ND

Post-infectious Syndromes, including Pediatric Autoimmune Neuropsychiatric Disorders associated with Streptococcal Infections (PANDAS) and Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), are autoimmune disorders that present with physiological, behavioural, and cognitive challenges. Acute onset of symptoms such as OCD, tics, anxiety, food restriction, bedtime fears, inability to control urination, aggression, deficits in learning, and social interaction are among the many manifestations of autoimmune encephalopathies and impair the daily functioning and cognitive progress of affected children.

These symptoms result from underlying infections, including Strep, Viruses, Mycoplasma, Tick-borne Illnesses, and other germs. Thorough clinical evaluation combined with a comprehensive integrative treatment approach focusing on antimicrobial, immune-modulating therapy, and symptomatic relief can transform pediatric post-infectious syndromes into treatable conditions.

Clinical Round | Resolving Stealth Infections

Todd LePine, MD

Dr Todd LePine explores clinical cases and integrative therapies to address stealth and co-infection. Nutritional considerations, nutraceuticals, and other interventional strategies will be examined to uncover and support patients with chronic, complex stealth, and co-infectious diseases.

Clinical Round | Pediatric Immunology

Lindsey Wells, ND and Nancy O’Hara, MD

Drs Lindsey Wells and Nancy O’Hara bring their expertise in pediatric care to this session, where the focus is on treatment strategies and protocols for PANDAs and post-infectious disorders in children. Case studies will be presented that demonstrate effective models for tackling these multi-faceted pathophysiological conditions.

LIVE Online Panel Review | Webinar Session

KEYNOTE: Emerging Therapies for the Chronic Sequelae of Infectious Disease

Matt Cook, MD

The long-term effects experienced by millions of patients recovering from COVID-19 serve as an impending health crisis potentially more significant than the initial infection itself. Chronic sequela that manifests as a result of viral and other infectious pathogens drive long-term healthcare costs, decreased quality of life, and poor health outcomes. Post-acute sequelae SARS-CoV-2 infection (PASC) is one area of chronic dysfunction for clinicians to address, with chronic fatigue syndrome/myalgic encephalomyelitis, Epstein-Barr, Lyme, and other co-infectious diseases imposing a heavy burden on presenting patients. Various novel therapies are emerging that demonstrate efficacy and early promise in supporting and treating the chronic sequela of infection disease. Pharmaceutical interventions, peptides, exosomes, and various nutraceutical and lifestyle interventions will be explored as effective offerings for clinicians seeking intervention in this population.

Emerging Evidence: Tocotrienol Research in 2022

Dr Barrie Tan, PhD

Identify the current state of science on vitamin E tocotrienols and potential contraindications. Apply clinical knowledge of tocotrienol’s benefits relevant to cardiovascular health, metabolic health (diabetes/pre-diabetes, fatty liver), anti-inflammation, and anti-oxidation. Recommend dosages for people with and without health issues.

A Naturopathic Approach to Lyme and Tickborne Infections

Myriah Hinchey, ND

The field of tick-borne disease (TBD) is complex and ever-evolving. With recent research providing measurable evidence of how Naturopathic medical interventions impact the initial infection and progression of TBD, functional medicine clinicians have a tremendous opportunity to change the course of a patient’s journey with Lyme disease and co-infections through individualized care in both the acute and chronic stages of illness. This lecture is an overview of the pathophysiology of Lyme disease-causing species of Borrelia as well as Babesia. It includes a deep dive into the biochemical pathways involved in infection, a four-pronged approach to treatment, and naturopathic interventions to support healing at every step.

Clinical Considerations and Protocols for Epstein Barr, Cytomegalo, and Human Herpesvirus-6

Christopher Bump, DC, MS, IFMCP, CNS

Laboratory diagnostic testing and the resulting recommended natural treatment protocols for common stealth infectious disorders: EBV, CMV, HSV, etc.

Chronic Immune Activation and HPV in Women’s Reproductive Health

Tabitha McIntosh, ND

HPV, chronic immune depletion, and cervical dysplasia ~ with an integrative/functional/Naturopathic slant on the various factors in the modern-day that impact our immune resilience.

Clinical Round | Long Haul COVID – Natural Medicine Interventions

David Brady, ND, DC

Dr David Brady translates the information shared in the CASI plenary sessions around Long Haul COVID Syndrome into a model for clinical intervention. Dr Brady addresses a variety of natural compounds, botanicals, and nutrients, as well as emerging biomedical solutions that mitigate the chronic sequelae associated with SARs-COv2.

Clinical Round | Gastroimmunology

Tom Fabian, PhD and Michael Jurgelewicz, DC

Drs Tom Fabian and Michael Jurgelewicz co-present on clinical strategies to support gastrointestinal function and the immunological interplay of GI disease on systemic health. Specific focus will be given to microbiome modulation, gut mucosal integrity, and gastroimmunological impact on digestive conditions and immunocompetency.

LIVE Online Panel Review | Webinar Session